A Cortisol test measures the level of cortisol, your body’s primary stress hormone. Cortisol is produced by the adrenal glands and affects metabolism, immune function, blood pressure, and stress response.
What This Test Measures
Cortisol:
A steroid hormone that follows a daily rhythm (highest in early morning, lowest at night). Cortisol helps regulate metabolism, immune response, blood sugar, and the body’s response to stress.
Reference Ranges
Morning (6-8 AM): 10-20 mcg/dL
Afternoon: 3-10 mcg/dL
Timing is critical – cortisol naturally varies throughout the day.
Who Should Consider This Test
• Chronic fatigue not explained by other causes
• Suspected adrenal insufficiency (Addison’s disease)
• Suspected Cushing’s syndrome (excess cortisol)
• Evaluating adrenal function
• Unexplained weight changes
• Chronic stress evaluation
• Symptoms of hormone imbalance
Understanding Results
High Cortisol May Indicate:
• Cushing’s syndrome
• Chronic stress
• Depression
• Obesity
• Excessive alcohol use
• Certain medications (steroids)
Low Cortisol May Indicate:
• Adrenal insufficiency (Addison’s disease)
• Pituitary dysfunction
• Long-term steroid use (adrenal suppression)
• Adrenal fatigue (controversial diagnosis)
Timing of Test
For most accurate results, test in the early morning (6-8 AM) when cortisol should be highest. Testing at other times may require different reference ranges.
How It Works
1. Order your test online – no doctor visit required
2. Visit any Quest Diagnostics location in the morning
3. Simple blood draw takes approximately 5 minutes
4. Results delivered to your secure portal within 1-2 business days
Preparation
No fasting required. Test in the early morning for standard reference ranges.
Related Tests to Consider
• DHEA-S – Another adrenal hormone
• Comprehensive Metabolic Panel – Overall health assessment
• Thyroid Panel – Can affect energy levels similarly
Why Choose Wittmer Rejuvenation Clinic
At $36, our Cortisol test is affordably priced. We partner with Quest Diagnostics for reliable, CLIA-certified laboratory testing.
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