Can Bacteriostatic Water Expire or Go Bad?

Can Bacteriostatic Water Expire or Go Bad?

Bacteriostatic water is widely used for reconstituting medications such as peptides, growth hormone, and semaglutide. But many users wonder—can bacteriostatic water expire or go bad? The short answer: yes. In this article, we explain why it has an expiration date, how to spot a compromised vial, and how to store it for maximum shelf life.

Does Bacteriostatic Water Expire?

Yes. Bacteriostatic water has two timelines to be aware of:

  • Unopened Vial: The expiration date is typically 2–3 years from the date of manufacture. This is listed on the vial.
  • Opened Vial: Once punctured, the water should be used within 28 days, per USP guidelines. After this, its sterility cannot be guaranteed.

Can It Go Bad Before Expiration?

Yes. Even before the labeled expiration date, bacteriostatic water can go bad if it is contaminated or stored improperly. Contaminants introduced during use or environmental exposure can make the solution unsafe for injection.

Signs That Your Bacteriostatic Water Has Gone Bad

  • Cloudy appearance
  • Visible particles or discoloration
  • Unusual odor
  • Vial open for more than 28 days

Proper Storage to Prevent Early Expiration

  • Keep the vial in a cool, dry place (68–77°F / 20–25°C)
  • Avoid exposure to direct sunlight or high humidity
  • Use sterile syringes and clean technique to draw the solution
  • Always label the date of first use

Why the 28-Day Rule Is Critical

Even with benzyl alcohol as a preservative, bacteriostatic water can lose effectiveness over time. After 28 days, the preservative may not be strong enough to prevent bacterial growth. Using expired or contaminated water increases the risk of infection and poor injection outcomes.

Need a Fresh Supply?

If your bacteriostatic water has expired or been open for longer than 28 days, it's time to replace it. Order a fresh vial here to ensure safe and sterile injection preparation.

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