A CBC with differential is a blood test that provides detailed information about the types and numbers of cells in your blood. The test measures various components of your blood, including red blood cells, white blood cells, and platelets. The differential portion of the test provides further information about the different types of white blood cells in your blood, including neutrophils, lymphocytes, monocytes, eosinophils, and basophils.
A CBC with differential can be used to help diagnose and monitor a wide range of medical conditions, including infections, anemia, leukemia, and other blood disorders. It can also be used to monitor the effects of certain medications or treatments on your blood cells. Your healthcare provider may order a CBC with differential if you are experiencing symptoms such as fatigue, weakness, fever, or unexplained bruising or bleeding.