Deamidated Gliadin Peptide IgG Blood Work Lab Test

A Deamidated Gliadin Peptide IgG (DGP-IgG) test is used to help diagnose celiac disease, an autoimmune disorder that affects the digestive system. Celiac disease occurs when the immune system mistakenly attacks gluten, a protein found in wheat, barley, and rye, causing inflammation and damage to the lining of the small intestine. The DGP-IgG test measures the levels of antibodies in the blood that are produced in response to gluten. Elevated levels of DGP-IgG antibodies are an indication that the immune system has mounted a response to gluten and may suggest the presence of celiac disease. The DGP-IgG test is often used in combination with other tests, such as the Deamidated Gliadin Peptide IgA (DGP-IgA) test and the tissue transglutaminase (tTG) test, to help confirm a diagnosis of celiac disease.