A DHEA-Sulfate (DHEA-S) test measures the level of dehydroepiandrosterone sulfate, a hormone produced primarily by the adrenal glands. DHEA-S serves as a precursor to both testosterone and estrogen.
What This Test Measures
DHEA-Sulfate (DHEA-S):
DHEA-S is the sulfated form of DHEA, which is more stable and present in higher concentrations in the blood. It’s the most abundant steroid hormone in the body and serves as a building block for sex hormones.
Reference Ranges
DHEA-S levels decline naturally with age. Ranges vary by sex and age:
Adult Men:
• Age 20-29: 280-640 mcg/dL
• Age 30-39: 120-520 mcg/dL
• Age 40-49: 95-530 mcg/dL
• Age 50+: Continues to decline
Adult Women:
• Age 20-29: 65-380 mcg/dL
• Age 30-39: 45-270 mcg/dL
• Age 40-49: 32-240 mcg/dL
• Age 50+: Continues to decline
Ranges vary by laboratory. Results should be interpreted by a healthcare provider.
Who Should Consider This Test
• Individuals experiencing symptoms of adrenal insufficiency
• Women with symptoms of excess androgens (acne, excess hair growth, irregular periods)
• Men or women with low energy, decreased libido, or mood changes
• Those evaluating PCOS (polycystic ovary syndrome)
• Adults interested in anti-aging hormone assessment
• People considering or taking DHEA supplements
• Those evaluating adrenal tumors (which can cause very high DHEA-S)
Why DHEA-S Matters
DHEA-S plays roles in:
• Production of testosterone and estrogen
• Immune function
• Energy and well-being
• Bone density
• Cognitive function
• Body composition
Low levels may contribute to fatigue, low libido, mood changes, and reduced well-being, particularly with aging.
How It Works
1. Order your test online – no doctor visit required
2. Visit any Quest Diagnostics location nationwide
3. Simple blood draw takes approximately 5 minutes
4. Results delivered to your secure portal within 1-2 business days
Preparation
No fasting required.
Related Tests to Consider
• Testosterone – DHEA-S converts to testosterone
• Cortisol – Another adrenal hormone
• Estradiol – DHEA-S converts to estrogen
• SHBG – Affects hormone availability
Why Choose Wittmer Rejuvenation Clinic
At $18.75, our DHEA-Sulfate test is competitively priced. As a hormone replacement therapy clinic, we understand adrenal hormones’ role in overall hormone balance. We partner with Quest Diagnostics for reliable, CLIA-certified laboratory testing with convenient locations across all 50 states.




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