A Thyroid Panel Comprehensive is a blood test that includes several markers of thyroid function, including:
Free T3: Triiodothyronine (T3) is one of the thyroid hormones that plays an important role in regulating metabolism and energy production. Free T3 is the active form of T3 that is not bound to protein and is available for use by the body.
Free T4: Thyroxine (T4) is another thyroid hormone that helps regulate metabolism and energy production. Free T4 is the active form of T4 that is not bound to protein and is available for use by the body.
TSH: Thyroid-stimulating hormone (TSH) is a hormone produced by the pituitary gland that stimulates the thyroid gland to produce T3 and T4. Elevated TSH levels can indicate an underactive thyroid (hypothyroidism), while low TSH levels can indicate an overactive thyroid (hyperthyroidism).
Thyroglobulin antibodies (TGA Abs) and Thyroid peroxidase antibodies (TPO Abs): These antibodies are produced by the immune system and can attack the thyroid gland, leading to autoimmune thyroid diseases such as Hashimoto’s thyroiditis and Graves’ disease. Measuring levels of TGA Abs and TPO Abs can help diagnose autoimmune thyroid diseases and monitor their progression.
Reverse T3 (RT3): Reverse T3 is a form of T3 that is inactive and cannot be used by the body. Elevated levels of RT3 may indicate a problem with the conversion of T4 to T3, which can affect thyroid function.
A Thyroid Panel Comprehensive is commonly ordered by doctors to evaluate thyroid function, diagnose thyroid disorders such as hypothyroidism and hyperthyroidism, and monitor the effectiveness of thyroid hormone replacement therapy. In addition to the markers included in the basic Thyroid Panel (Free T3, Free T4, and TSH), the Thyroid Panel Comprehensive also includes measures of thyroid antibodies and RT3, which can provide additional information about thyroid function and autoimmune thyroid diseases.
It’s important to discuss your symptoms and medical history with your doctor to determine the appropriate tests and treatments for your individual situation.